2020 – 2025

2025

  • Guzmán-Rodríguez, M., Hernández-Díaz, T., Lisboa, P., López-Schettini, J., Sanhueza, S., Leyton, L., Iwawaki, T., Soto-Rifo, R., Osorio, F. “The IRE1/XBP1s Axis Regulates Innate Immune Responses in Conventional Dendritic Cells During ZIKV Infection”. FASEB J. 2025 Sep 15;39(17):e71025. Abstract Link
  • Simón, L., Torres, K., Guerrero, S., Oyarzun-Ampuero, F., Quest, A.F.G. “Curcumin-loaded nanoemulsions and phloroglucinol target hexokinase 2 to inhibit Caveolin-1-induced glycolysis and metastasis in cancer cells”. Biomed Pharmacother. 2025 Aug;189:118339. Epub 2025 Jul 15. Open Access Link
  • Cabeza, C., Rojas, F., Lobos-González, L., Lemaitre, D., Villena, J., Cordero, M.L., Hassan, N., Ortiz, R. “Capture and detection of extracellular vesicles derived from human breast cancer cells using a 3D self-assembled nanostructured SiO2 microfluidic chip”. J Biol Eng. 2025 Jul 29;19(1):71. PubMed Link – Open Access Link
  • Bolaños, K., León, D., Jara-Guajardo, P., Contreras, P., Silva Ancahuail, D., Riveros, A.L., Montano, Y., Pérez, D., Araya, E., Kogan, M.J., Quest, A.F.G. “In vivo Targeted Delivery of Extracellular Vesicle‒Gold Nanorod Hybrids to Metastatic Melanoma Lung Tumors”. Int J Nanomedicine. 2025 May 30;20:6983–6998. PubMed Link – Open Access Link
  • Huilcaman, R., Campos, A., Contreras, P., Simón, L., Varas-Godoy, M., Grünenwald, F., Baohai Shao, Jay Heinecke, Lobos-Gonzalez, L., Leyton, L. & Quest, A.F.G. “Inclusion of ΑVβ3 integrin into extracellular vesicles in a caveolin-1 tyrosine-14- phosphorylation dependent manner and subsequent transfer to recipient melanoma cells promotes migration, invasion and metastasis”. Cell Communication and Signaling, 2025 March 17, Volume 23, Article 139. Open Access Link
  • Mora-Lagos, B., Reyes, M.E., Lobos-Gonzalez, L., Del Campo, M., Buchegger, K., Zanella, L., Riquelme, I., Ili, C.G. & Brebi, P. “Maraviroc/cisplatin combination inhibits gastric cancer tumoroid growth and improves mice survival”. Biol Res. 2025 Jan 18;58(1):4. PubMed Link – Open Access Link
  • Peña-Oyarzún, D., Quest A.F.G., Lobos-González, L., Maturana-Ramírez, A., Reyes, M. “Porcupine expression promotes the progression of oral carcinogenesis”. Neoplasia 59 (2025) 101097. Jan:59:101097. PubMed Link – Open Access Link
  • Cifuentes, M., Verdejo, H.E., Castro, P.F., Corvalán, A.H., Ferreccio, C., Quest, A.F.G., Kogan, M.J., Lavandero, S. “Low-grade Chronic Inflammation: A Shared Mechanism for Chronic Diseases”. Physiology (Bethesda). 2025 Jan 1;40(1):0. Epub 2024 Jul 30. Abstract Link

2024

  • González-Turén, F., Lobos-González, L., Riquelme-Herrera, A., Ibacache, A., Meza Ulloa, L., Droguett, A., Alveal, C., Carrillo, B., Gutiérrez, J., Ehrenfeld, P., Cárdenas-Oyarzo, A. “Kinin Receptors B1 and B2 Mediate Breast Cancer Cell Migration and Invasion by Activating the FAK-Src Axis”. Int J Mol Sci. 2024 Oct 31;25(21):11709. PubMed Link – Open Access Link
  • Pérez, L.A., Palacios, E., González, M.F., Leyton-Rivera, I., Martínez-Meza, S., Pérez-Núñez, R., Jeldes, E., Avalos, A.M., Díaz, J., Leyton, L. “A Pro-Inflammatory Stimulus versus Extensive Passaging of DITNC1 Astrocyte Cultures as Models to Study Astrogliosis”. Int. J. Mol. Sci. 2024, Volume 25, Issue 17, 9454. 2024 August 30. Open Access Link
  • Simón, L., Torres, K., Contreras, P., Díaz-Valdivia, N., Leyton, L., Quest, A.F.G. “Inhibition of glycolysis and Src/Akt signaling reduces Caveolin-1-enhanced metastasis”. Biomed Pharmacother. 2024 Jul:176:116841. Open Access Link
  • Donoso-González, O., Riveros, A.L., Marco, J.F., Venegas-Yazigi, D., Paredes-García, V., Olguín, C.F., Mayorga-Lobos, C., Lobos-González, L., Franco-Campos, F., Wang, J., Kogan, M.J., Bollo, S., Yañez, C., Báez, D.F.“Iron-Reduced Graphene Oxide Core-Shell Micromotors Designed for Magnetic Guidance and Photothermal Therapy under Second Near-Infrared Light”. Pharmaceutics. 2024 Jun 25;16(7):856. PubMed Link – Open Access Link
  • Fierro-Arenas, A., Landskron, G., Camhi-Vainroj, I., Basterrechea, B., Parada-Venegas, D., Lobos-González, L., Dubois-Camacho, K., Araneda, C., Romero, C., Domínguez, A., Vásquez, G., López-K, F., Alvarez, K., González, C.M., Hager Ribeiro, C., Balboa, E., Eugenin, E., Hermoso, M.A., De la Fuente López, M.“Pannexin-1 expression in tumor cells correlates with colon cancer progression and survival”. Life Sci. 2024 Aug 15;351:122851. Epub 2024 Jun 17. Open Access Link
  • Pérez-Núñez, R., González, M.F., Avalos, A.M., Leyton, L. “Impacts of PI3K/protein kinase B pathway activation in reactive astrocytes: from detrimental effects to protective functions”. Neural Regen Res. 2025 Apr 1;20(4):1031-1041. Epub 2024 Jun 3. Open Access Link
  • Yáñez, L., Soto, C., Tapia, H., Pacheco, M., Tapia, J., Osses, G., Salinas, D., Rojas-Celis, V., Hoare, A., Quest, A.F.G., Díaz-Elizondo, J., Pérez-Donoso, J.M., Bravo, D. “Co-Culture of P. gingivalis and F. nucleatum Synergistically Elevates IL-6 Expression via TLR4 Signaling in Oral Keratinocytes”. Int J Mol Sci. 2024 Mar 23;25(7):3611. PubMed Link – Open Access Link
  • Peña-Oyarzún, D., Flores, T., Torres, V.A., Quest, A.F.G., Lobos-Gonzalez, L., Kretschmar, C., Orellana, P., Maturana, A., Criollo, A., Reyes, M.“Inhibition of PORCN blocks Wnt signaling to attenuate progression of oral carcinogenesis”. Clin Cancer Res. 2024 Jan 5;30(1):209-223. Clinical Cancer Research Link
  • Durán-Jara, E., Del Campo, M., Gutiérrez, V., Wichmann, I., Trigo, C., Ezquer, M., Lobos-González, L. “Lactadherin immunoblockade in small extracellular vesicles inhibits sEV-mediated increase of pro-metastatic capacities”. Biol Res. 2024 Jan 3;57(1):1. PubMed Link – Open Access Link

2023

  • Paredes, F., Navarro-Marquez, M., Quiroga, C., Jiménez-Gallegos, D., Yeligar, S.M., Parra, V., Müller, M., Chiong, M., Quest, A.F.G., San Martin, A., Lavandero, S. “HERPUD1 governs tumor cell mitochondrial function via inositol 1,4,5-trisphosphate receptor-mediated calcium signaling”. Free Radic Biol Med. 2023 Dec 2:211:24-34. Open Access Link
  • Valdivia, A.D.*, Ávalos, A.M., Leyton, L.* “Thy-1(CD90)-regulated cell adhesion and migration of mesenchymal cells: Insights into Adhesomes, Mechanical Forces, and Signaling Pathways”. Front. Cell Dev. Biol.; Sec. Cell Adhesion and Migration, Volume 11 – 2023. *Corresponding authors (equal contribution). November 30th, 2023. Open Access Link
  • Lobos-González, L., Oróstica, L., Díaz-Valdivia, N., Rojas-Celis, V., Campos, A., Duran-Jara, E., Farfán, N., Leyton, L., Quest, A.F.G. “Prostaglandin E2 Exposure Disrupts E-Cadherin/Caveolin-1-Mediated Tumor Suppression to Favor Caveolin-1-Enhanced Migration, Invasion, and Metastasis in Melanoma Models”. Int J Mol Sci. 2023 Nov 29;24(23):16947. PubMed Link – Open Access Link
  • Campos, A., Burgos-Ravanal, R., Lobos-González, L., Huilcamán, R., González, M.F., Díaz, J., Verschae, A.C., Acevedo, J.P., Carrasco, M., Sepúlveda, F., Jeldes, E., Varas-Godoy, M., Leyton, L., Quest, A.F.G. “Caveolin-1-dependent tenascin C inclusion in extracellular vesicles is required to promote breast cancer cell malignancy”. Nanomedicine (Lond). 2023 Oct;18(23):1651-1668. Epub 2023 Nov 6. PubMed Link
  • Hidalgo, A., Bravo, D., Soto, C., Maturana, G., Cordero-Machuca, J., Zúñiga-López, M.C., Oyarzun-Ampuero, F., Quest, A.F.G. “The Anti-Oxidant Curcumin Solubilized as Oil-in-Water Nanoemulsions or Chitosan Nanocapsules Effectively Reduces Helicobacter pylori Growth, Bacterial Biofilm Formation, Gastric Cell Adhesion and Internalization”. Antioxidants (Basel). 2023 Oct 16;12(10):1866. PubMed Link – Open Access Link
  • Macuer-Guzmán, J., Giovagnoli-Vicuña, C., Bernal, G., Lobos-González, L., de la Fuente-Ortega, E., Araya-Castillo, M., Ibáñez, C. “Annona cherimola Seed Extracts Trigger an Early Apoptosis Response and Selective Anticlonogenic Activity against the Human Gastric Carcinoma Cell Line SNU-1”. Molecules. 2023 Oct 2;28(19):6906. PubMed Link – Open Access Link
  • Simón, L., Arazo-Rusindo, M., Quest, A.F.G., Mariotti-Celis, M.S “Phlorotannins: Novel Orally Administrated Bioactive Compounds That Induce Mitochondrial Dysfunction and Oxidative Stress in Cancer”. Antioxidants (Basel). 2023 Sep 7;12(9):1734. PubMed Link – Open Access Link
  • Sepúlveda, F., Mayorga-Lobos, C., Guzmán, K., Durán-Jara, E., Lobos-González, L. “EV-miRNA-Mediated Intercellular Communication in the Breast Tumor Microenvironment”. Int J Mol Sci. 2023 Aug 23;24(17):13085. PubMed Link – Open Access Link
  • Maldonado H., Leyton, L. “CSK-mediated signalling by integrins in cancer”. Front Cell Dev Biol. 2023 Jul 7;11:1214787. PubMed Link – Open Access Link
  • Palacios, E., Lobos-González, L., Guerrero, S., Kogan, M.J., Shao, B., Heinecke, J.W., Quest, A.F.G., Leyton, L., Valenzuela-Valderrama, M. “Helicobacter pylori outer membrane vesicles induce astrocyte reactivity through nuclear factor-κappa B activation and cause neuronal damage in vivo in a murine model”. J Neuroinflammation. 2023 Mar 9;20(1):66. PubMed Link – Open Access Link – Springer Link
  • Pérez-Núñez, R., Chamorro, A., González, M.F., Contreras, P, Artigas, R., Corvalán, A.H., van Zundert, B., Reyes, C., Moya, P.R., Avalos, A.M., Schneider, P., Quest, A.F.G. & Leyton, L. “Protein kinase B (AKT) upregulation and Thy-1-αvβ3 integrin-induced phosphorylation of Connexin43 by activated AKT in astrogliosis”. J Neuroinflammation. 2023 Jan 6;20(1):5. PubMed Link – Open Access Link – Springer Link
  • Sanhueza, S., Simón, L., Cifuentes, M., Quest, A.F.G. “The Adipocyte–Macrophage Relationship in Cancer: A Potential Target for Antioxidant Therapy”. Antioxidants. 2023 Jan 4;12(1), 126. PubMed Link – Open Access Link

2022

  • Díaz-Vesga, M.C., Flores-Vergara, R., Riquelme, J.A., Llancaqueo, M., Sánchez, G., Vergara, C., Michea, L., Donoso, P., Quest, A.F.G., Olmedo, I., Pedrozo, Z. “Polycystin-1 Is a Crucial Regulator of BIN1 Expression and T-Tubule Remodeling Associated with the Development of Dilated Cardiomyopathy”. Int J Mol Sci. 2022 Dec 30;24(1):667. PubMed Link – Open Access Link
  • Neira-Carrillo, A., Zárate, I.A., Nieto, E., Butto-Miranda, N., Lobos-González, L., Del Campo-Smith, M., Palacio, D.A., Urbano, B.F.“Electrospun Poly(acrylic acid- co-4-styrene sulfonate) as Potential Drug-Eluting Scaffolds for Targeted Chemotherapeutic Delivery Systems on Gastric (AGS) and Breast (MDA-Mb-231) Cancer Cell Lines”. Nanomaterials (Basel). 2022 Nov 4;12(21):3903. PubMed Link – Open Access Link
  • Pérez, L.A., León, J., López, J., Rojas, D., Reyes, M., Contreras, P., Quest, A.F.G., Escudero, C., Leyton, L. “The GPI-Anchored Protein Thy-1/CD90 Promotes Wound Healing upon Injury to the Skin by Enhancing Skin Perfusion”. Int J Mol Sci. 2022 Oct 19;23(20):12539. PubMed Link – Open Access Link
  • González, M.F., Burgos-Ravanal, R., Shao, B., Heinecke, J., Valenzuela-Valderrama, M., Corvalán, A.H., Quest, A.F.G. “Extracellular vesicles from gastric epithelial GES-1 cells infected with Helicobacter pylori promote changes in recipient cells associated with malignancy.”. Front Oncol. 2022 Oct 12;12:962920. PubMed Link – Open Access Link
  • Soto, C., Rojas, V., Yáñez, L., Hidalgo, A., Olivera, M., Pacheco, M., Venegas, D., Salinas, D., Bravo, D., Quest, A.F.G. “Porphyromonas gingivalis-Helicobacter pylori co-incubation enhances Porphyromonas gingivalis virulence and increases migration of infected human oral keratinocytes”. J Oral Microbiol. 2022 Aug 12;14(1):2107691. PubMed Link
  • Díaz-Valdivia, N., Simón, L., Díaz, J., Martinez-Meza, S., Contreras, P., Burgos-Ravanal, R., Pérez, V.I., Frei, B., Leyton, L., Quest, A.F.G. “Mitochondrial Dysfunction and the Glycolytic Switch Induced by Caveolin-1 Phosphorylation Promote Cancer Cell Migration, Invasion, and Metastasis”. Cancers (Basel). 2022 Jun 10;14(12):2862. PubMed Link – Open Access Link
  • Hu, P., Leyton, L., Hagood, J.S., Barker, T.H. “Thy-1-Integrin Interactions in cis and Trans Mediate Distinctive Signaling”. Front Cell Dev Biol. 2022 Jun 6;10:928510. PubMed Link – Open Access Link
  • Simón, L., Sanhueza, S., Gaete-Ramírez, B., Varas-Godoy, M., Quest, A.F.G. “Role of the Pro-Inflammatory Tumor Microenvironment in Extracellular Vesicle-Mediated Transfer of Therapy Resistance”. Front Oncol. 2022 May 11;12:897205. PubMed Link – Open Access Link
  • Salas-Huenuleo, E., Hernández, A., Lobos-González, L., Polakovičová, I., Morales-Zavala, F., Araya, E., Celis, F., Romero, C., Kogan, M.J. “Peptide Targeted Gold Nanoplatform Carrying miR-145 Induces Antitumoral Effects in Ovarian Cancer Cells”. Pharmaceutics. 2022 Apr 28;14(5):958. PubMed Link – Open Access Link
  • Morales, F., Pérez, P., Tapia, J.C., Lobos-González, L., Herranz, J.M., Guevara, F., de Santiago, P.R., Palacios, E., Andaur, R., Sagredo, E.A., Marcelain, K., Armisén, R. “Increase in ADAR1p110 activates the canonical Wnt signaling pathway associated with aggressive phenotype in triple negative breast cancer cells”. Gene. 2022 Apr 20;819:146246. Epub 2022 Feb 2. Open Access Link
  • Castro, I., Carvajal, P., Jara, D., Aguilera, S., Heathcote, B., Barrera, M.J., Aliaga-Tobar, V., Maracaja-Coutinho, V., Urzúa, U., Quest, A.F.G., González, S., Molina, C., Hermoso, M., González, M.J. “Small RNA Expression Profiling Reveals hsa-miR-181d-5p Downregulation Associated With TNF-α Overexpression in Sjögren’s Syndrome Patients”. Front Immunol. 2022 Apr 1;13:870094. PubMed Link – Open Access Link
  • Arrua, E.C., Sanchez, S.V., Trincado, V., Hidalgo, A., Quest, A.F.G., Morales, J.O. “Experimental design and optimization of a novel dual-release drug delivery system with therapeutic potential against infection with Helicobacter pylori”. Colloids Surf B Biointerfaces. 2022 Feb 11;213:112403. Open Access Link
  • Pérez, L.A., Leyton, L., Valdivia, A. “Thy-1 (CD90), Integrins and Syndecan 4 are Key Regulators of Skin Wound Healing”. Front. Cell Dev. Biol. 2022 Feb 03;10:810474. PubMed Link – Open Access Link

2021

  • Garrido, M.P., Fredes, A.N., Lobos-González, L., Valenzuela-Valderrama, M., Vera, D.B., Romero, C. “Current Treatments and New Possible Complementary Therapies for Epithelial Ovarian Cancer”. Biomedicines. 2021 Dec 31;10(1):77. PubMed Link – Open Access Link
  • Pérez, L.A., Rashid, A., Combs, J.D., Schneider, P., Rodríguez, A., Salaita, K. and Leyton, L. “An Outside-In Switch in Integrin Signaling Caused by Chemical and Mechanical Signals in Reactive Astrocytes”. Front. Cell Dev. Biol. 2021 Aug 23;9:712627. PubMed Link – Open Access Link
  • Zárate, A.M., Espinosa-Bustos, C., Guerrero, S., Fierro, A., Oyarzún-Ampuero, F., Quest, A.F.G., Di Marcotullio, L., Loricchio, E., Caimano, M., Calcaterra, A., González-Quiroz, M., Aguirre, A., Meléndez, J., Salas, C.O. “A New Smoothened Antagonist Bearing the Purine Scaffold Shows Antitumour Activity In Vitro and In Vivo”. Int J Mol Sci. 2021 Aug 4;22(16):8372. PubMed Link – Open Access Link
  • Burgos-Ravanal, R., Campos, A., Díaz-Vesga, M.C., González, M.F., León, D., Lobos-González, L., Leyton, L., Kogan, M.J., Quest, A.F.G. “Extracellular Vesicles as Mediators of Cancer Disease and as Nanosystems in Theranostic Applications”. Cancers (Basel). 2021 Jul 2;13(13):3324. PubMed Link – Open Access Link
  • Ortega, L., Lobos-González, L., Reyna-Jeldes, M., Cerda, D., De la Fuente-Ortega, E., Castro, P., Bernal, G., Coddou, C. “Corrigendum to «The Ω-3 fatty acid docosahexaenoic acid selectively induces apoptosis in tumor-derived cells and suppress tumor growth in gastric cancer» [Eur. J. Pharmacol. (2021) 173910]”. Eur J Pharmacol. 2021 Sep 5;906:174287. Epub 2021 Jun 25. Open Access Link
  • González, M.F., Díaz, P., Sandoval-Bórquez, A., Herrera, D., Quest, A.F.G. “Helicobacter pylori Outer Membrane Vesicles and Extracellular Vesicles from Helicobacter pylori-Infected Cells in Gastric Disease Development”. Int J Mol Sci. 2021 May 1;22(9):4823. PubMed Link – Open Access Link
  • Sandoval-Bórquez, A., Polakovicova, I., Carrasco-Véliz, N., Lobos-González, L., Riquelme, I., Carrasco-Avino, G., Bizama, C., Norero, E., Owen, G.I., Roa, J.C., Corvalán, A.H. “Correction to: MicroRNA-335-5p is a potential suppressor of metastasis and invasion in gastric cancer”. Clin Epigenetics. 2021 Mar 8;13(1):50. PubMed Link – Open Access Link
  • Díaz, P., Sandoval-Bórquez, A., Bravo-Sagua, R., Quest, A.F.G., Lavandero, S. “Perspectives on Organelle Interaction, Protein Dysregulation, and Cancer Disease”. Front Cell Dev Biol. 2021 Feb 25;9:613336. PubMed Link – Open Access Link
  • Ortega, L., Lobos-González, L., Reyna-Jeldes, M., Cerda, D., De la Fuente-Ortega, E., Castro, P., Bernal, G., Coddou, C. “The Ω-3 fatty acid docosahexaenoic acid selectively induces apoptosis in tumor-derived cells and suppress tumor growth in gastric cancer”. Eur J Pharmacol. 2021 Apr 5;896:173910. Epub 2021 Jan 26. Open Access Link
  • Brenet, M., Martínez, S., Pérez-Nuñez, R., Pérez, L.A., Contreras, P., Díaz, J., Avalos, A.M., Schneider, P., Quest, A.F.G. and Leyton, L. “Thy-1 (CD90)-Induced Metastatic Cancer Cell Migration and Invasion Are β3 Integrin-Dependent and Involve a Ca2+/P2X7 Receptor Signaling Axis”. Front. Cell Dev. Biol. 2021 Jan 12;8:592442. PubMed Link – Open Access Link
  • Díaz, P., Román, A., Carrasco-Aviño, G., Rodríguez, A., Corvalán, A.H., Lavandero, S. and Quest, A.F.G. “Helicobacter Pylori Infection Triggers PERK-Associated Survivin Loss in Gastric Tissue Samples and Cell Lines”. J Cancer Sci Clin Ther 2021; 5 (1): 063-082. Open Access Link

2020

  • Rivas, S., Silva, P., Reyes, M., Sepúlveda, H., Solano, L., Acuña, J., Guerrero, M., Varas-Godoy, M., Quest, A.F.G., Montecino, M., Torres, V.A. “The RabGEF ALS2 is a hypoxia inducible target associated with the acquisition of aggressive traits in tumor cells”. Sci Rep. 2020 Dec 18;10(1):22302. PubMed Link – Open Access Link
  • Rosa, L., Lobos-González, L., Muñoz-Durango, N., García, P., Bizama, C., Gómez, N., González, X., Wichmann, I.A., Saavedra, N., Guevara, F., Villegas, J., Arrese, M., Ferreccio, C., Kalergis, A.M., Miquel, J.F., Espinoza, J.A., Roa, J.C. “Evaluation of the chemopreventive potentials of ezetimibe and aspirin in a novel mouse model of gallbladder preneoplasia”. Mol Oncol. 2020 Nov;14(11):2834-2852. Epub 2020 Sep 17. PubMed Link – Open Access Link
  • Lara, P., Chan, A.B., Cruz, L.J., Quest, A.F.G., Kogan, M.J. “Exploiting the Natural Properties of Extracellular Vesicles in Targeted Delivery towards Specific Cells and Tissues”. Pharmaceutics. 2020 Oct 26;12(11):1022. PubMed Link – Open Access Link
  • Garrido, M.P., Salvatierra, R., Valenzuela-Valderrama, M., Vallejos, C., Bruneau, N., Hernández, A., Vega, M., Selman, A., Quest, A.F.G., Romero, C. “Metformin Reduces NGF-Induced Tumour Promoter Effects in Epithelial Ovarian Cancer Cells”. Pharmaceuticals (Basel). 2020 Oct 16;13(10):315. PubMed Link – Open Access Link
  • Garrido, M.P., Torres, I., Avila, A., Chnaiderman, J., Valenzuela-Valderrama, M., Aramburo, J., Oróstica, L., Durán-Jara, E., Lobos-Gonzalez, L., Romero, C. “NGF/TRKA Decrease miR-145-5p Levels in Epithelial Ovarian Cancer Cells”. Int J Mol Sci. 2020 Oct 16;21(20):7657. PubMed Link – Open Access Link
  • Orellana-Serradell, O., Díaz, M.C., González, M.F., Gutiérrez, M., Herrera, D., Jara, D., Maureira, D., Ruiz-Fuentes, J.L., Sanhueza, Leyton, L. “Does Peer Reviewing for COVID-19-Related Papers Still Work?”. Front. Res. Metr. Anal., 08 October 2020. Open Access Link – Sbcch Link – News Link
  • Burgos-Bravo, F., Martínez-Meza, S., Quest, A.F.G., Wilson, C.A.M. and Leyton, L. “Application of Force to a Syndecan-4 Containing Complex With Thy-1–αVβ3 Integrin Accelerates Neurite Retraction”. Front. Mol. Biosci., 29 September 2020. Open Access Link
  • Sanhueza, C., Castillo-Bennett, J., Valenzuela-Valderrama, M., Contreras-Orellana, P., Lobos-González, L., Campos, A., Wehinger, S., Lladser, A., Kiessling, R., Leyton, L., Quest, A.F.G. “Caveolin-1-Mediated Tumor Suppression Is Linked to Reduced HIF1α S-Nitrosylation and Transcriptional Activity in Hypoxia”. Cancers 2020;12(9), 2349. 2020 Aug 20. PubMed Link – Open Access Link
  • Valdivia, A., Cárdenas, A., Brenet, M., Maldonado, H., Kong. M., Díaz, J., Burridge, K., Schneider, P., San Martín, A., García-Mata, R., Quest, A.F.G., Leyton, L. “Syndecan-4/PAR-3 signaling regulates focal adhesion dynamics in mesenchymal cells”. Cell Communication and Signaling. 2020 Aug 18;18(1):129. PubMed Link – Open Access Link – News Link
  • Díaz, M.I., Díaz, P., Castillo Bennett, J., Urra, H., Ortiz, R., Contreras-Orellana, P., Hetz, C., Quest, A.F.G. “Caveolin-1 suppresses tumor formation through the inhibition of the unfolded protein response”. Cell Death and Disease. 2020 Aug 03;11:648. PubMed Link – Open Access Link
  • Lillo, P., Núñez, O., Castro-Sepúlveda, M., Torres-Quintana, M.A., Lladser, A., Quest, A.F.G., Espinoza, C., Llanos, P., Wehinger, S. “Loss of Caveolin-1 Is Associated with a Decrease in Beta Cell Death in Mice on a High Fat Diet”. Int J Mol Sci. 2020 Jul 23;21(15):E5225. PubMed Link
  • Palavecino, C.E., Carrasco-Véliz, N., Quest, A.F.G., Garrido, M.P., Valenzuela-Valderrama, M. “The 5′ untranslated region of the anti-apoptotic protein Survivin contains an inhibitory upstream AUG codon”. Biochem Biophys Res Commun. 2020 Apr 9. pii: S0006-291X(20)30658-6. PubMed Link
  • Simón, L., Campos, A., Leyton, L. & Quest, A.F.G. “Caveolin-1 function at the plasma membrane and in intracellular compartments in cancer”. Cancer Metastasis Rev 39, 435–453. 2020 May 27. Open Access Link – News Link
  • De Gregorio, C., Contador, D., Díaz, D., Cárcamo, C., Santapau, D., Lobos-Gonzalez, L., Acosta, C., Campero, M., Carpio, D., Gabriele, C., Gaspari, M., Aliaga-Tobar, V., Maracaja-Coutinho, V., Ezquer, M., Ezquer, F. “Human adipose-derived mesenchymal stem cell-conditioned medium ameliorates polyneuropathy and foot ulceration in diabetic BKS db/db mice”. Stem Cell Res Ther. 2020 May 1;11(1):168. PubMed Link – Open Access Link
  • Ortiz, R., Díaz, J., Díaz-Valdivia, N., Martínez, S., Simón, L., Contreras-Orellana, P., Lobos-González, L., Guerrero, S., Leyton, L., Quest, A.F.G. “Src-family kinase inhibitors block early steps of caveolin-1-enhanced lung metastasis by melanoma cells”. Biochem Pharmacol. 2020 Mar 30;177:113941. Open Access Link
  • Ferreccio, C., Huidobro, A., Cortés, S., Bambs, C., Toro, P., Van De Wyngard, V., Acevedo, J., Paredes, F., Venegas, P., Verdejo, H., Oyarzún-González, X., Cook, P., Castro, P.F., Foerster, C., Vargas, C., Koshiol, J., Araya, J.C., Cruz, F., Corvalán, A.H., Quest A.F., Kogan, M.J., Lavandero, S., MAUCO Study Group. “Cohort Profile: The Maule Cohort (MAUCO)”. Int J Epidemiol. 2020 Mar 16. pii: dyaa003. PubMed Link
  • Díaz-Valdivia, N.I., Díaz, J., Contreras-Orellana, P., Campos, A., Rojas-Celis, V., Burgos-Ravanal, R.A., Lobos-González, L., Torres, V.A., Perez, V.I., Frei, B., Leyton, L., Quest, A.F.G. “The non-receptor tyrosine phosphatase type 14 blocks caveolin-1-enhanced cancer cell metastasis”. Oncogene. 2020 Mar 9;39(18):3693–3709. Sbcch Link – PubMed Link
  • Villa, M., Cerda-Opazo, P., Jimenez-Gallegos, D., Garrido-Moreno, V., Chiong, M., Quest, A.F., Toledo, J., Garcia, L. “Pro-fibrotic effect of oxidized LDL in cardiac myofibroblasts”. Biochem Biophys Res Commun. 2020 Apr 9;524(3):696-701. Epub 2020 Feb 6. PubMed Link
  • Lara, P., Palma-Florez, S., Salas-Huenuleo, E., Polakovicova, I., Guerrero, S., Lobos-Gonzalez, L., Campos, A., Muñoz, L., Jorquera-Cordero, C., Varas-Godoy, M., Cancino, J., Arias, E., Villegas, J., Cruz, L.J., Albericio, F., Araya, E., Corvalan, A.H., Quest, A.F.G., Kogan, M.J. “Gold nanoparticle based double-labeling of melanoma extracellular vesicles to determine the specificity of uptake by cells and preferential accumulation in small metastatic lung tumors”. J Nanobiotechnology. 2020 Jan 23;18(1):20. PubMed Link – Open Access Link
  • Borgna, V., Lobos-González, L., Guevara, F., Landerer, E., Bendek, M., Ávila, R., Silva, V., Villota, C., Araya, M., Rivas, A., López, C., Socias, T., Castillo, J., Alarcón, L., Burzio, L.O., Burzio, V.A., Villegas, J. “Targeting antisense mitochondrial noncoding RNAs induces bladder cancer cell death and inhibition of tumor growth through reduction of survival and invasion factors”. J Cancer. 2020 Jan 17;11(7):1780-1791. eCollection 2020. PubMed Link – Journal of Cancer Link
  • Lagos-Cabré, R., Burgos-Bravo, F., Avalos, A.M., Leyton, L. “Connexins in Astrocyte Migration”. Front Pharmacol. 2020 Jan 15;10:1546. PubMed Link
  • Lobos-González, L., Bustos, R., Campos, A., Silva, V., Silva, V., Jeldes, E., Salomon, C., Varas-Godoy, M., Cáceres-Verschae, A., Duran, E., Vera, T., Ezquer, F., Ezquer, M., Burzio, V.A., Villegas, J. “Exosomes released upon mitochondrial ASncmtRNA knockdown reduce tumorigenic properties of malignant breast cancer cells”. Sci Rep. 2020 Jan 15;10(1):343. PubMed Link
Comparte: